Dr. Nikolay Yu. Gorobets
2005 – 2006
National Academy of Science of Ukraine. Grant of National Academy of Sciences of Ukraine
General test of microwave system EmrysTM Creator EXP was perfomed. An efficient multi-component method for 2-amino-5,6-dihydropyrimidin-4(3H)-ones under conventional and microwave condition was developed. A fast microwave-assisted one-pot synthesis of benzopyrano[2,3-c]pyrazoles was proposed. A reaction of 3-aminotriazole, acetone and salicylic aldehydes derivatives was found to lead to a novel oxygen-bridge heterocyclic system that could not be obtained under usual conditions.
The project results are published:
Ostras, K. S.; Gorobets, N. Yu.; Desenko, S. M.; Musatov, V. I. An easy access to 2-amino-5,6-dihydro-3H-pyrimidin-4-one building blocks: The reaction under conventional and microwave conditions, Molecular Diversity, 2006, 10, 483
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